Intravenous lipid emulsion: Why wait to save a life?
نویسندگان
چکیده
منابع مشابه
Failure of Intravenous Lipid Emulsion to Reduce Diazinon-induced Acute Toxicity: a Pilot Study in Rats
Diazinon (DZN) is a synthetic organophosphorus (OPs) insecticide widely used in agricultural and household applications. OPs, particularly DZN, are highly lipid soluble liquids. Intravenous lipid emulsion (ILE) has been shown to reduce toxicity caused by some lipid soluble agents. We evaluated the antidote effect of ILE on acute toxicity of DZN. Twenty-four Sprague-Dawley female rats weightin...
متن کاملFailure of Intravenous Lipid Emulsion to Reduce Diazinon-induced Acute Toxicity: a Pilot Study in Rats
Diazinon (DZN) is a synthetic organophosphorus (OPs) insecticide widely used in agricultural and household applications. OPs, particularly DZN, are highly lipid soluble liquids. Intravenous lipid emulsion (ILE) has been shown to reduce toxicity caused by some lipid soluble agents. We evaluated the antidote effect of ILE on acute toxicity of DZN. Twenty-four Sprague-Dawley female rats weightin...
متن کاملReview of Intravenous Lipid Emulsion Therapy
Intravenous fat emulsion (IVFE) is an important source of calories and essential fatty acids for patients receiving parenteral nutrition (PN). Administered as an individual infusion or combined with PN, the fats provided by IVFE are vital for cellular structural function and metabolism. The affinity of some medications to lipids has led to the use of IVFE as a treatment for any lipophilic drug ...
متن کاملIntravenous lipid emulsion in clinical toxicology
Intravenous lipid emulsion is an established, effective treatment for local anesthetic-induced cardiovascular collapse. The predominant theory for its mechanism of action is that by creating an expanded, intravascular lipid phase, equilibria are established that drive the offending drug from target tissues into the newly formed 'lipid sink'. Based on this hypothesis, lipid emulsion has been con...
متن کاملWait, save that integrin!
RNF169 flips the repair switch P oulsen et al. describe an enzyme that helps a cell determine which repair method to use on DNA double-strand breaks (DSBs). Unrepaired DSBs can incite genomic chaos, spurring sections of chromosomes to relocate or even vanish. To ensure that doesn’t happen, a cell wraps a molecular bandage around a DSB. Enzymes arrive at the injury and ubiquitylate the surroundi...
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ژورنال
عنوان ژورنال: Emergency Medicine Australasia
سال: 2011
ISSN: 1742-6731
DOI: 10.1111/j.1742-6723.2011.01400.x